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25 Castelli MC, Friedman K, Sherry J et al (2011) Comparing the efficacy and tolerability of a new daily oral vitamin B12 formulation and intermittent intramuscular vitamin B12 in normalizing low cobalamin levels: a randomized, open-label, parallel-group study
If you're very low in B12, you can get higher-dose vitamin B12 shots
How Deep Should a B12 Injection Go
or if you are receiving any medication or treatment that affects bone marrow
Additionally, certain antibiotics and anticonvulsants can increase B12 metabolism, reducing its efficacy period