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689 With the consumption of GPX4, SLC7A11 and GSH, a significant increase in total iron and lipid peroxidation could be detected within 2 weeks

4 In a follow-up study, researchers found that supplementing with vitamins B12 and B9 (folic acid) may increase the risk of colon cancer

Based on these data, it can be assumed that, the rapid inhibition of Na,K-ATPase in the red blood cells, concomitant with an increase of 1.62 times in the level of endogenous TSs in the blood is attributable to the low Na,K-ATPase content and the presence of highly affine 3-isoform ( As demonstrated in (Zhang et al., 2018), the lifespan of red blood cells is reduced in chronic kidney disease (CKD), a disease accompanied by increased CTS levels in the blood (Orlov et al., 2021)

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