Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
As a research-grade compound, it provides a standardized tool for exploring these complex biological phenomena
In panel B, the red areas show the neurofilament light chain (NfL) concentration that reveals a similar negative relationship with NDI, indicating neurodegeneration
The primers used for cloning are shown in Supplementary Data 5
Another Parkinsonian model employing 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) toxicity found that UA could reduce oxidative stress, inflammation, and dopaminergic neuronal dysfunction in the brain 35
This supplement is especially useful for individuals who suffer from cramps during exercise or need to improve endurance and recovery