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At the same time, it can also oxidize and integrate detoxification

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NOS-dependent NO production is facilitated by three tissue-specific NOS isozymes, namely, nNOS, eNOS, and iNOS ( Stimulation of NO production via the NOS-dependent pathway nNOS and eNOS are calciumcalmodulin-dependent enzymes responsible for the conversion of L-arginine and oxygen to L-citrulline and NO (Ignarro, 1990

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