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Funding This work was supported by grants from Fundao Carlos Chagas Filho de Amparo Pesquisa do Estado do Rio de Janeiro (FAPERJ), Coordenao de Aperfeioamento de Pessoal de Nvel Superior (CAPES) and Conselho Nacional de Desenvolvimento Cientfico e Tecnolgico (CNPq)

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4b) by DPI and the absence of such inhibition by antioxidants such as ascorbic acid, the peroxynitrite-scavenger uric acid, ebselen, and even the spin-trap TEMPONE-H (Suppl