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[17] [18] Glibenclamide may occasionally be considered under specialist supervision when other options are unsuitable, with careful monitoring of the infant for signs of hypoglycaemia (poor feeding, jitteriness, unusual sleepiness)

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The increased understanding of activation pathways and related ECD conformations may inspire the design of new molecules targeting the ECDECL interface

It also warns that cannabis-driven appetite changes can be mistaken for the medication working or failing