As a general clinical principle: Retest HbA1c no sooner than three months after commencing B12 replacement therapy, and ideally once haematological recovery has been confirmed Confirm haematological recovery normalisation of MCV and haemoglobin before interpreting the repeat HbA1c as reliable Use interim glucose monitoring such as fasting plasma glucose, OGTT, or self-monitored blood glucose (SMBG) to assess glycaemic control during the treatment period
untreated sham 218 22 g/g
Therefore, combining GLP-1 RAs with SGLT2 inhibitors in clinical practice may be a strategy to leverage the benefits of each agent for MACE and HF respectively
Glutathione is also a constituent in the regulation of protein and gene expression, exchange reactions including thiol to disulfide ratios involve glutathione.4 Glutathione can exist intracellularly in either an oxidized (glutathione disulfide) or reduced (glutathione) molecular state
If so, Klarity Health is a great place to start
10.1016/j.brainres.2010.04.080 Brain Res