WALKER, A.I.T., BLAIR, D., STEVENSON, D.E., & CHAMBERS, P.L
Forbes J, Munakomi S, Cronovich HA, Romberg T
How PlexusDx Supports a More Personalized Approach PlexusDx's Precision Peptide Genetic Test may help provide context regarding metabolic enzyme variants and antioxidant pathways relevant to medication processing
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In a culture obsessed with weight and food, some patients find that GLP-1s provide a welcome, healthy break from food noise and allow them to focus their attention elsewhere
The two primary MTHFR variants are C677T (rs1801133) which substitutes valine for alanine at position 222, reducing enzyme activity by approximately 35% in heterozygotes and 70% in T/T homozygotes at physiological folate concentrations and A1298C (rs1801131) which substitutes glutamate for alanine at position 429, reducing activity by approximately 20% in heterozygotes, with compound heterozygosity (C677T + A1298C) producing effects between the two individual homozygous states
