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Learn where to self-administer a B12 shot and how to do it painlessly This article was medically reviewed by Shari Forschen, NP, MA and by wikiHow staff writer, Amber Crain

According to the NIH Office of Dietary Supplements, vitamin B12 is available as cyanocobalamin and hydroxocobalamin, which are typically administered parenterally by intramuscular injection to bypass gastrointestinal absorption barriers

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