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134 established a link between the increased expression, and changes in the localisation, of SOP enzymes and suppression of the growth-restricting effects of excess H 2 S in colorectal carcinoma cells

We can indirectly assume ozone therapy influenced synthesis and release of cytokines (18,19) in such a way that a change from Th2 to Th1 (IL-2, IFNg) cytokine pattern occurs, or ozone therapy acted as Th2 cytokine inhibitor