& Daniels, S
Frequent vomiting can dehydrate you, especially during the adjustment period when youre still getting used to the medications effects
The primary cause for alarm is thyroid C-cell hyperplasia, which has been the subject of FDA boxed warnings since a research conducted on rats showing dose-dependent C-cell tumors (Madsen et al
These results directly challenge the assumption that glucagon receptor activation must necessarily impair weight-loss pharmacotherapy
Used together in appropriately selected women, HRT (started within the timing window) and a GLP-1 agonist may offer additive cardiovascular protection through complementary mechanisms: estrogen via favorable lipid effects and vascular function, GLP-1 agonists via blood pressure reduction, weight loss, and direct cardiac effects [36]
Purely from a value perspective, we should be even more underallocating here, but I feel that we might be betting on Novo Nordisk a bit too much