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Choosing lighter options can significantly reduce overall calorie intake

It is whether the strategy improves brain function without worsening overall stability

NICE technology appraisal TA875 (2023) recommends semaglutide 2.4 mg (Wegovy) as an adjunct to a reduced-calorie diet and increased physical activity for adults with a BMI of 35 kg/m or above (or 3034.9 kg/m in certain circumstances) alongside at least one weight-related comorbidity, when initiated within specialist weight management services

For example, two medications that both lower blood pressure could, when taken together, lead to an excessive drop in blood pressure

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