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Laboratory investigations have reported measurable changes in nitric oxide related signaling markers, endothelial migration assays, fibroblast gene expression profiles, and cytoskeletal reorganization markers in cell culture and animal models

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Inject the water slowly down the inside wall of the vial, gently swirl until dissolved, and refrigerate at 36-46F

Once reconstituted, tirzepatide must be stored in the refrigerator at a temperature between 36F and 46F (2C to 8C)

Unlike sterile water, which is single-use, bacteriostatic water is designed for multi-dose use because the benzyl alcohol prevents bacterial growth in the vial