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In IBD, chronic inflammation disrupts this stabilitypathogenic bacteria (e.g., Ruminococcus gnavus ) proliferate rapidly, while beneficial taxa (e.g., Faecalibacterium prausnitzii ) decline, leading to chaotic microbial fluctuations and reduced diversity (30, 32)

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Following incubation, beads were washed once with cold KPBS (pH=7.25) before being incubated in 200 l transport buffer (KPBS+10 mM HEPES + 0.5 mM EGTA) at room temperature containing indicated doses of [ 13 C 2 , 15 N]-GSH (Cambridge Isotope Laboratory, CNLM-6245-50) for the indicated times

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They are listed here as a reference for researchers investigating BPC-157