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Some key players have been well-characterized, but other aspects of the signalling mechanisms involved are still unclear
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Discontinuation rates across trials: Retatrutides discontinuation rate in the general obesity population (11.3%) is higher than its approved competitors
Electrolytes like magnesium and potassium play a key role in muscle function
The without-DAC version, by contrast, produces a single GH pulse that resolves within 2-3 hours
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