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This strategy relies on the higher concentration of reducing molecules such as glutathione in the cytoplasm (110 mmol/L) (Wu et al., 2004) compared to the extracellular environment (about 5 mol/L in blood) (Mills and Lang, 1996)

This makes plant-based sources excellent options for those concerned about overconsumption

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Circ Res 2020;127:486-501

It reduces the activity of skin cells that make dark pigments (melanin)