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Also, in patients who have an eGFR 60 mL/min/1.73 m 2 and who tolerate 100 mg once daily, the canagliflozin dose can be increased to 300 mg once daily if additional glycemic control is needed [45]

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Considering our ratesetting methodology and prior experiences implementing new data, we issued a follow-up from the CY 2023 PFS comment solicitation for general information