Yang, H., et al., Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappaB and AP-1
Researchers study it for fat-cell shrinkage, higher NAD+ levels, and metabolic support without affecting appetite
Finally, partial inhibition of GSH may induce stress responses in cancer cells, leading to the upregulation of detoxifying enzymes and drug resistance
The effect on vessel formation in transected tendons has been documented morphologically across multiple Sikiric lab publications, though precise fold-change numbers vary by study and tissue type
Potential Benefits: Accelerated healingof muscles, tendons, ligaments, and bones
Antioxidants 10:1491