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[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Poston L., Briley A., Seed P., Kelly F., Shennan A

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Semaglutide is sold under three brand names, each with slightly different dosing profiles: Ozempic injectable, once-weekly, approved for type 2 diabetes and cardiovascular risk reduction Wegovy injectable, once-weekly, higher dose (up to 2.4 mg), approved for weight management Rybelsus oral tablet, taken daily, approved for type 2 diabetes All three share the same active ingredient and similar side-effect profiles, though Wegovy at higher doses tends to cause more frequent GI symptoms

Reviewed on Nov 21, 2025