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Each of the FDA-approved GLP-1Ms have been prescribed at VUMC (Supplemental Table 3), although the prevalence for each varied
We conducted qPCR analysis of the aforementioned genes, foxo1a , ppargc1a , and eif4ebp3l , and confirmed their expressions are associated with the improved muscle endurance and swim speed with the drug treatments in the LMNA transgenic zebrafish
It did not produce the magnitude of weight loss we now consider transformative, which is why it never became a mainstream drug
Its important to note that these dosages may vary based on individual patient factors, such as weight, age, and overall health status