Providing a treatment option that is proven to lower this cardiovascular risk is a major advance for public health. The FDAs decision is largely based on data from the SELECT trial, which included more than 17,000 overweight or obese patients with a baseline age of 45 years old
Sterile water has no preservative, limiting your vial to a single use
People are starting to embrace this burgeoning GLP-1 era, but with so many supplements on the market, choosing the right one for you can feel overwhelming
GLP-1R activation of neuroprotective pathways in neurons, microglia and astrocytes has also been reported: improvements in overall cognition, learning and motor function potentially associated with GLP-1RA administration in Alzheimers disease and Parkinsons disease may be mediated not only by their amyloid pathology-ameliorating properties (A, tau and -synuclein), but also the suppression of Ca 2+ deregulation and endoplasmic reticulum stress, anti-inflammatory activity, blockage of oxidative stress, mitochondrial dysfunction and apoptosis pathways, enhancements in the neuronal insulin sensitivity and energy metabolism, functional improvements in autophagy and mitophagy, elevated brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor synthesis, and neurogenesis 36
This article breaks down what we know so far, explains the science behind the hype, and outlines what it means for people living with diabetes today
Xie Y, Wang SX, Sha WW, Zhou X, Wang WL, Han LP, et al
