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Safety, Medical Supervision, and Who Should Use GLP-1 Therapy GLP-1 medications carry potential side effects (nausea, gastrointestinal symptoms, rare pancreatitis risk) that require baseline medical evaluation and ongoing provider monitoring

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Its glucagon-receptor arm may favor energy expenditure and fat mobilization, but "increases fat loss" is not the same as "builds muscle." Any muscle gain during use would come from training and protein, not the drug

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In HS, the expression and activity of MMP-2, 8 and 9 are significantly dysregulated [74, 93, 94] (Fig