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JakobssonJEMenezesJKrockEHuntMACarlssonHVaivadeAet alFibromyalgia patients have altered lipid concentrations associated with disease symptom severity and anti-satellite glial cell IgG antibodies

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The substantial weight loss achieved with GLP-1 receptor agonists and dual GIP/GLP-1 agonistsapproximately 15% with semaglutide 2.4 mg (Wegovy) and up to 21% with higher doses of tirzepatide (Zepbound) in clinical trialsoccurs primarily through appetite suppression and reduced caloric intake rather than increased metabolic rate

Additional safety considerations include: risk of hypoglycemia when used with insulin or sulfonylureas (dose adjustments may be needed)

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