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10.1016/s0140-6736(14)60802-3 46 HartyL

The imbalance between the antioxidant defense system and the generation of oxidants creates oxidative stress which can further cellular damage and compound adverse issues from chronically impaired sleep such as obesity and even neurodegenerative disorders

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Prior studies involving diet and bariatric surgery have already demonstrated meaningful reductions in knee pain and disability following substantial weight reduction

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