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**Considering a GLP-1 medication for weight loss?** Licensed providers on Klarity Health can evaluate your eligibility and prescribe online no in-person visit needed

The inability to sustain weight loss may be due to PYY 3-36 -induced Y2-R down-regulation and tolerance (i.e., tachyphylaxis) and/or activation of compensatory mechanisms in response to reduced food intake

They can indicate potentially serious conditions that need prompt diagnosis and treatment

Many patients assume peptide therapy simply involves receiving a prescription

Discuss all risks thoroughly with a qualified surgeon

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