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The gut is impacted

Strasser B, Spreitzer A, Haber P

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Looking ahead, the next phase of obesity medicine will likely see GLP-1 medications used in combination with other weight loss agents, as well as expanded research into their effects on conditions like high blood pressure, heart attack risk, and liver disease

Semaglutide-related diarrhea tends to persist slightly longer during dose escalation, likely because the higher weight-loss dose takes longer to reach steady state

Obstructive sleep apnea is directly linked to daytime somnolence, cognitive impairment, and decreased quality of life, and has been associated with broader health conditions, including high blood pressure, heart attacks, heart failure, and diabetes