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Another factor contributing to Cavity II closure is the positioning of Met 5.39

Comparison of multiple mean values was evaluated by One-way ANOVA followed by post-hoc Bonferroni test

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These findings suggest that GIP but not GLP-1RA may improve glucose disposal by ameliorating peripheral insulin sensibility and glucose utilization, while GIP added on to GLP-1RA may reduce food intake with a combined effect resulting in improvement of glucose control and weight loss