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Brelstaff, J., Tolkovsky, A

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Rodents with induced hippocampal lesions, scopolamine-induced amnesia, or age-related cognitive decline show robust dose-dependent improvements

The pH was adjusted to 2.2, 5 mL of thioglycolic acid was added and the volume was brought to 1 L

7.2 Nose-to-brain delivery of exendin-4 and insulin using penetratin Having established that intranasal insulin/L-penetratin administration was effective at mild stage of cognitive dysfunction but not at severe cognitive dysfunction in senescence-accelerated mice (Kamei et al., 2018), this group investigated the effectiveness of GLP-1 receptor agonist, exendin-4, in modulating severe cognitive impairment

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