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Common symptoms of vitamin B12 deficiency: Fatigue and a subjective feeling of low energy levels Hair loss and changes in skin color (usually manifests as pale skin) Brain and cognitive issues like decreased memory, depressive-like symptoms, mood changes, and brain fog Shortness of breath or difficulty with sustained exercise Megaloblastic anemia Depression and even a dementia-like syndrome can be confused with Alzheimers Nerve conditions like nerve pain and peripheral neuropathy Why are the symptoms so diverse