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2002 Oct 11;51(40):897-9 Mei Z, et al

The peptide appears to promote mucosal healing through enhancement of epithelial cell proliferation and migration, restoration of tight junction integrity, and modulation of inflammatory responses within the gastrointestinal tract

It worked: the patients pain was relieved

The expression of GPX4 was rescued after co-transfection with miRNA and GPX4 mut (the expression vector of GPX4 with a mutated miRNA-targeting site) (Figure 2I)

What would move this position is: a randomised, placebo-controlled trial in a defined population with an objective primary endpoint, a pre-registered protocol, and pharmacovigilance over a clinically meaningful duration

This hypothesis is supported by observed increases in prolactin levels among DFP-treated patients, suggesting a reduced dopaminergic activity (Devos et al., 2022)