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Then, the [2,3]-sigmatropic rearrangement of INT1-S via TS1-S forms an ortho -S = N substituted dearomatized species INT2-S , with a barrier of 9.7 kcal mol 1

On the one hand, ID represents a major cause of hypothyroidism worldwide, and it also favors the development of goiter and thyroid nodules [6, 17, 23]

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Constitutive expression is mediated by an adjacent AP-1 site