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Oxidative stress, along with structural changes such as axonal loss and demyelination from toxic insults like hyperglycemia and alcohol consumption, are also associated factors

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doi: 10.1371/journal.pone.0129898 85 BlombergJGottfriesCGElfaitouriARizwanMRosnA

However, preclinical research was stopped because of hepatotoxicity after a phase II clinical trial (Holubarsch et al., 2007)

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Fujimura M, Usuki F (2022) Cellular conditions responsible for methylmercury-mediated neurotoxicity