10.1038/s41586-020-2269-x 118
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Lack of Human Clinical Data: Despite growing concern about MNP exposure, direct evidence from human clinical studies remains extremely limited
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The known inhibitor tiopronin (glutathione analogue) was also investigated in a similar way and was observed to have the expected orientation within the active site
Hyperhomocysteinemia-Mediated Homocysteinylation Inconsistent with the hypothesis of an increased oxidant stress, a decrease in LDL susceptibility to oxidation and in plasma peroxidation indicators was reported in homozygous patients for CBS deficiency (Blom et al, 1992, 1995