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Vitamin B12 injections are not weight-loss treatments
According to Plumbs Veterinary Handbook, a common recommended dose for injectable cyanocobalamin for treating B12 deficiency is 25mcg/kg
Risk factors that should prompt consideration of B12 deficiency include advancing age (reduced stomach acid production), strict vegan or vegetarian diets, pernicious anaemia, gastrointestinal surgery (particularly gastric bypass or ileal resection), long-term use of certain medications (metformin, proton pump inhibitors, H2-receptor antagonists), nitrous oxide exposure (including recreational use), and conditions affecting the gut such as Crohn's disease or coeliac disease
Yes, vitamin B12 injections can help with fatigue, especially if your tiredness is linked to a B12 deficiency
Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system