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Its an active organ that can release inflammatory molecules, disrupt hormones, and trigger insulin resistance by quietly changing your metabolism, mood, and even your brain function

Treatment of human and mouse small intestine organoid models with SCFAs increases the number of GLP-1-producing cells twofold 284 , and SCFA infusion activates colonic EECs to increase GLP-1 release in mice 281

Cho S, Mutlu L, Grechukhina O, Taylor HS

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It's a natural hormone produced in your gut that plays a crucial role in how your body manages appetite, digestion, and blood sugar levels

doi: 10.1126/scitranslmed.adp0004 113 RoeK