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The compound has the molecular formula C 33 H 57 N 11 O 9 , a weight of 751.87 g/mol, and CAS number 129954-34-3

At 265 lb, exposure ran 25% to 30% lower. On that class-based model, 1 mg in a 155 lb person can approximate the exposure produced by 1.5 mg in the 240 lb trial cohort

Bepirovirsen, developed by GlaxoSmithKline (GSK), is a 2-MOE-modified ASO that targets all HBV RNAs, promoting RNase H-mediated RNA degradation, reducing HBV replication, and inhibiting HBsAg production