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Vitamin B12 is also vital to the nervous system and helps metabolize fat, protein, and carbohydrates

due to aging of the brain

Similarly, intrahippocampal infusions of IL-6 induced IDO1 expression, and inhibition of hippocampal IDO1 ameliorated depressive-like behavior in male rats [115]

In addition, a case-control study ( n = 257 cases, 133 controls) in 1993 reported that lower riboflavin intake, assessed via 24 h dietary recall, was associated with increased risk of cervical intraepithelial dysplasia, an early stage proceeding invasive cervical cancer 139

Frontiers in Genetics

Kwiatkowski 2009