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High doses of B12, often used to treat deficiencies, may cause side effects such as headaches, nausea, diarrhea, fatigue or weakness, and tingling in the hands and feet

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This type of study is important for several reasons: it tells us how long the peptide remains active in the body, what breakdown products are formed (which could themselves have biological activity or be used as markers in drug testing), and helps explain why AOD9604 needs to be administered in certain ways to remain effective

Orhan I, Aydin S, Altin G, Yilmaz F