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pharmacokinetic data show bupropion SR peaks around 3 hours (StatPearls)

Klein ME, Dabbs DJ, Shuai Y, Brufsky AM, Jankowitz R, Puhalla SL, Bhargava R

Discuss pregnancy, planned pregnancy, or breastfeeding with a healthcare professional

Safe alternatives include gradual dietary modification following the NHS Eatwell Guide, regular physical activity (150 minutes weekly of moderate-intensity exercise), and NHS weight management programmes

Meticulous sun protection avoid going outdoors during the sunniest period of the day, use umbrellas, hats and protective clothing, and apply sunscreen regularly 4

However, other studies have suggested that GLP-1 drugs increase the risk of diabetic retinopathy or exacerbate it in those who already have it