We have seen in our office patients losing anywhere from 4-12 pounds the first month, and around 20-30 pounds within 3-4 months
That means youre less likely to confuse GLP-1/GIP side effects like nausea, constipation, or fatigue with thyroid symptoms, and you have the Paloma team looking at the full picture rather than treating each issue separately
Laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass lead to equal changes in body composition and energy metabolism 17 months postoperatively: a prospective randomized trial
Relative risk vs absolute risk Heres a hypothetical example of what we mean: well use a fake drug, known as drug X
By synthesizing trial outcomes, labeling guidance, and clinical practice considerations, this comparison supports providers in determining which medication aligns best with an individual patients metabolic profile, treatment goals, and risk factors
Reducing this risk is a key part of our commitment to driving change for this community, as we work to increase manufacturing capacity to responsibly supply this important medicine. The FDA decision is based on the results of the landmark SELECT phase 3 cardiovascular outcomes trial that examined the effect of adding Wegovy 2.4mg or placebo to cardiovascular standard of care in adults with overweight and obesity with established cardiovascular disease and without diabetes