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Translational barriers and clinical limitations of CSC-targeted therapies A representative summary of clinical trials and approved CSC-targeting agents, including pathway inhibitors, immune therapies, and metabolic modulators, is provided in Table 1

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The anti-inflammatory properties of glutathione can also help calm irritated skin and reduce redness, making it particularly beneficial for those dealing with post-inflammatory hyperpigmentation from acne or other skin concerns

Bergapten effectively treats CARAS mice by increasing the levels of IgE, IgG1, IL-12, IFN-, IL-10, and Foxp3 while downregulating the levels of IL-4, IL-5, IL-13, IL-17, and RORt [173]