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She told Today, Explained co-host Jonquilyn Hill that it isnt quite depression, but more of a missing spark, making people lose interest in things they previously loved

J Med Chem 43:49985002 Grieco P, Cai M, Liu L, Mayorov A, Chandler K, Trivedi D, Lin G, Campiglia P, Novellino E, Hruby VJ (2008) Design and microwave-assisted synthesis of novel macrocyclic peptides active at melanocortin receptors: discovery of potent and selective hMC5R receptor antagonists

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The findings in the present work contribute to understanding the metabolic and molecular mechanisms behind tamoxifen resistance in breast cancer

In some cases, yes