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The ideal therapeutic compound for TBI and CNS diseases should have PK-PD criteria such as smaller molecular weight, moderately lipophilic, low plasma protein binding affinity, higher distribution volume, and serve as weak ligand of P-glycoprotein or another efflux pump located at the BCB [44]

Vitamin C helps convert the spent glutathione back into its active, "reduced" state so it can go back to work

"It should be used only for short periods to quell acute nausea, not chronically to permit rapid dose escalation

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It plays a crucial role in regulating appetite, blood sugar levels, and insulin sensitivity

Early and precise interventions, using a comprehensive systems-biology approach, are vital for improving overall health outcomes