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Indicated in unexplained infertility and mild male factor Synchronisation with ovulation improves fertilisation probability High-Yield Revision Points Letrozole = Drug of choice in PCOS ovulation induction Clomiphene = SERM with anti-estrogenic effects Gonadotropins = Highest efficacy but highest risk (OHSS, multiples) Follicle size for trigger = 1820 mm Clomiphene resistance = No ovulation at 150 mg dose Ovulation induction protocols form a critical component of infertility management , integrating reproductive physiology with pharmacological intervention

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