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Hypoxia stress was modeled by placing rats into a flow pressure chamber for 15 minutes under 0.26 bar, which simulates an altitude of 10,000 m above ground level

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[DOI] [PubMed] [Google Scholar] 4.Peto R, Davies C, Godwin J, Gray R, Pan HC, Clarke M, et al

Additionally, it shows a greater ability to inhibit tyrosinase activity (an enzyme that produces melanin and causes hyperpigmentation) than other antioxidants used in skin care, such as kojic acid 2

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