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Dose-adjusted DOACs have been primarily examined in randomized controlled trials (RCTs) to prevent stroke in specific subgroups of patients with AFib, such as patients with advanced age, low body weight, renal dysfunction, and/or drug interactions
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I've also seen a protocol where
For instance, a recent study conducted by Babu Balagopal et al 26 has reported reductions in liver enzyme levels in 13 patients with NAFLD after 16 weeks of NAC treatment
Third, potential compensatory changes in other mitochondrial carriers following SLC25A39 knockout should be considered, future studies exploring chronic adaptations in carrier networks will be valuable
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