Questions to Ask Your Doctor If Youre Thinking About Stopping GLP-1 Medication If you are considering discontinuing GLP-1 therapy, it may be helpful to discuss: What is the best approach to tapering off
Check with HR or the plan document for indication-specific coverage
Rubino F, Cummings DE, Eckel RH, Cohen RV, Wilding JPH, Brown WA, et al
Creatine, Exercise, and GLP-1: A Synergistic Effect Exercise itself stimulates GLP-1 release
Ongoing support, every step of the way Check in with your doctor regularly to ensure your plan is working for you
Pharmacokinetics of tirzepatide demonstrated dose proportionality over the wide dose range, with C max of 180 nM in individuals treated with one dose of 8 mg and a C max of 260 nM with 15 mg/week dose in the clinical study, exceeding the EC50 values for GIPR and GLP-1R activations by approximately 10,000-fold and 250-fold, respectively (63)