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Switching between GLP-1 medications There are a few reasons why your clinician may suggest switching GLP-1s

Be sure to add the solvent(s) in order

Improved glycemic control In adults with type 2 diabetes, weekly semaglutide lowered long-term blood sugar (HbA1c) by about 1.5 points, while placebo barely moved (The Lancet Diabetes & Endocrinology, 2017)

Whatever your concentration is, move the decimal one place to the left, and that is your milligram dose for 10 units

After 3 to 4 months on tirzepatide, if its specific side effects (perhaps insomnia or different GI patterns) become problematic, returning to semaglutide allows your body to reset from tirzepatide-specific effects

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