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Data are presented as the mean standard deviation

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It belongs to the class of growth hormone-releasing hormones (GHRH) and acts by stimulating the pituitary gland to produce more growth hormone, which can have various positive effects, including lean muscle mass growth, fat metabolism, and overall anti-aging benefits

It is responsible for much of the anabolic activity of growth hormone, including nitrogen retention and protein synthesis as well as muscle cell hyperplasia (increase in number of muscle cells), as well as mitogenesis (the growth of new muscle fibers)

164 Crucially, mTORC1 also acts as a primary regulator of eEF2K, 165 exemplified by the numerous downstream targets of AMPK that are directly phosphorylated by mTORC1 or S6K1, to counteractively modulate their functions in relation to AMPK phosphorylation

Antonissen et al., 2015)