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Consistency and lifestyle factors greatly influence outcomes

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Clinical trial durations: Most obesity studies used daily dosing for 12 weeks Wellness clinic use: Often structured in 8-week cycles, followed by reassessment before continuing

DMSO consistently showed effects different from the water control both at the mRNA and protein level of estrogenic target genes/proteins

It also demonstrated the counteraction of the adverse effects of either NOS blockade (L-NAME) or NOS substrate L-arginine application (i.e., it opposed hypertension and pro-thrombotic effects (L-NAME) [26,55], as well as hypotension and anti-thrombotic (L-arginine) effects [26,55])